This study aimed to investigate the relationship between happiness and gratitude among the female administrative staff at University in Riyadh, in light of some demographic variables, this is due to the limited research addressing the relationship between these two variables among this occupational group in the Saudi university context. The study sample consisted of 640 female administrative employees. The descriptive-analytical method was employed, and the Oxford Happiness Questionnaire (OHQ) and the Gratitude Resentment and Appreciation Test (GRAT) were administered. The findings displayed a high level of happiness among the participants and moderate-to-high levels of gratitude among the majority of the sample. A statistically significant positive correlation was also found between the happiness and gratitude at the 0.01 significance level. Furthermore, no statistically significant differences in happiness were found according to years of experience, whereas a significant difference were found according to age and marital status. The level of gratitude was also varied according to some demographic variables. Finally, the study recommends using these findings to develop counseling and training programs that encourage happiness and gratitude in the university work environment.