The study aimed to explore the relationship among Psychological Self-sufficiency, meaning in life, and psychosocial adjustment among unmarried women in the Gaza Strip. A descriptive-correlational methodology was employed. The study sample consisted of 141 unmarried women. The researchers used self-developed scales to measure Psychological Self-sufficiency, meaning in life, and psychosocial adjustment. The results indicated that the relative weight of Psychological Self-sufficiency was 73.9%, meaning in life was 82.6%, and psychosocial adjustment was 78.5%. The study revealed statistically significant relationships between Psychological Self-sufficiency (and its dimensions) and psychosocial adjustment, between meaning in life (and its dimensions) and psychosocial adjustment, and between psychological well-being and meaning in life among the participants. No statistically significant differences in Psychological Self-sufficiency were found attributable to the variable of having children; however, significant differences were observed based on social status. Conversely, no statistically significant differences in meaning in life were associated with social status, yet significant differences were found based on whether participants had children. The researchers recommended that the Ministry of Social Development conduct training workshops and awareness programs for unmarried women to equip them with recovery and coping strategies.